Saturday, October 15, 2016

How Mast Cell Activation Disorder and Histamine Intolerance May Be Affecting Your Recovery From Lyme Disease

When Infection Triggers an Auto-Inflammatory Reaction

Lyme disease is the fastest growing vector-borne disease in the U.S. today with an estimated 329,000 Americans affected annually. Studies have shown that anywhere from 10-60% of patients who are treated with a standard course of antibiotics for Lyme Disease, will have continuing, sometimes debilitating symptoms. The CDC calls this chronic condition "Post Treatment Lyme Disease Syndrome" (PTLDS). There is a growing body of evidence that demonstrates the reason for this condition may be due to an undiagnosed co-infection (like babesia bartonella, ehrlichia or anaplasma)[1] and/or treatment resistant Lyme bacteria, also known as persistent infection. (see my prior post on Lyme Persisters) The other possibility is that the infection triggers a dysfunction within the immune system. This can lead to an autoimmune or auto-inflammatory disease separate from or in addition to the infection. In this post I will be exploring how Lyme Disease can trigger an auto-inflammatory reaction through Mast Cell Activation.







How The Immune System Reacts to Infection

Some people with impaired immune systems may not immediately detect an infection, allowing for a delay in the immune response. Other invaders, especially those that are slow growers like HIV, Leprosy, TB and Lyme may have a sub-clinical phase during which the immune system fails to recognize the stealth infection allowing it to disseminate throughout the body.

The immune system is divided into two categories called Innate Immunity and Adaptive Immunity. The innate immune system is the early defense mechanisms that activate when a foreign invader enters the body. The adaptive (or acquired) system is more complex in that it is able to recognize antigens on the outside of foreign agents and create an immune response that is specific to that infection. The adaptive system also forms memory cells capable of responding to future attacks.

Early in the onset of an infection, the causative agent (virus, bacteria, protozoa, etc...) will provoke changes in a healthy immune system. This is called an immune response. Whenever cells or tissues of the body are injured or infected there is a resulting inflammatory response. Inflammation causes a vascular reaction with the purpose of delivering blood and healing nutrients to the area of injury. 




How Lyme Disease Hides in Connective Tissue

Lyme Disease is caused by Borrelia burgdorferi a corkscrew shaped bacterium with an affinity for connective tissue[2]. Connective tissue is the most widely distributed, varied type of tissue found in the human body. It includes: loose connective tissue (epithelia, fascia, pleura, pericardial sac, esophagus, and the outer covering of blood vessels, nerves, and brain.); fat (adipose tissue); dense irregular connective tissue (skin, capsules around organs and fibrous sheath around bones); dense regular connective tissue (tendons and ligaments); cartilage (ear, larynx, joints, between ribs, intervertebral discs); bone (skeleton); and blood (erythrocytes, leukocytes, and platelets). 

Borrelia is known to spread to the Lymphatic system within the first 24 hours after infection.[3]  During inflammation the lymphatic channels will maintain in an open position not only increasing flow of protein and lymphatics but also inadvertently spreading infectious agents. From the lymphatic system Borrelia will move to collagen rich areas of the body. Collagen is a type of connective tissue found in skin, bone, tendon, cartilage, synovium, the walls of blood vessels and the outer covering of nerves. (see my prior post on Decorin and Collagen

What Are Mast Cells

The mast cell is an immune sentinel or "guard" that originates from stem cells in the bone marrow. It is found abundantly in the skin, respiratory tract, gastrointestinal and genitourinary tracts, but can also be found in clusters next to small blood vessels, the nervous system, and in loose connective tissue where Lyme likes to hide (see above). The purpose of a mast cell is to alert the immune system to outside invaders (wounds, bacteria, viruses, bee stings, allergens, etc). The surface of the mast cell is covered with IgE receptors which are very sensitive to allergens and parasites. When a foreign antigen comes into contact with the mast cell it will trigger the release of the contents of the mast cell. One of the contents is histamine, a powerful vasodilator which affects vascular permeability, smooth-muscle contraction, and secretion of certain mucosal cells. The histamine alerts the immune system which then helps to defend and clear the body of pathogens and allergens. If too many mast cells are activated at once the patient will undergo a life-threatening inflammatory reaction called anaphylaxis.[4




What Is Histamine

Histamine is a vasoactive mediator, chemically known as a biogenic amine. There are five biogenic amine neurotransmitters: dopamine, norepinephrine, epinephrine, serotonin and histamine. Histamine acts to mediate arousal and attention, as well as producing pro-inflammatory signals from mast cells to various cells within the immune system. These cells include macrophages, dendrites, T-lymphocytes, B-lymphocytes, endothelia, and antigen specific Th1 and Th2 T-helper cells. Histamine is responsible for stimulating stomach acid (HCL) and contributes to vasodilation and increased vascular permeability. Large amounts of Histamine are stored within the mast cells that are present in the granules of connective tissues.

There are four basic histamine receptors in the body: H1, H2, H3 and H4 which I have highlighted below:

click to enlarge



Histamine is broken down by methyl compounds therefore high histamine levels may cause depleted methyl groups. Methylation defects (MTHFR) may lead to inability to clear histamine which may lead to histamine intolerance and a host of other disorders. In the central nervous system histamine is metabolized by Histamine N-methyltransferase (HNMT), and in the digestive tract it is broken down by Diamine oxidase (DAO) enzymes.  Patients with low DAO levels are at increased risk for histamine intolerance (DAO SNP's can be seen on 23andME or diagnosed if plasma levels are below 10kU/L). Low DAO can be a result of genetics, or caused by gluten intolerance, leaky gut, SIBO, Crohn's, ulcerative colitis, and inflammatory bowel disease. [5] In addition to histamine, mast cells release a number of inflammatory mediators. I have included a partial list below:


click to enlarge

How Does Infection Trigger Mast Cell Activation

While mast cells are primarily known for detecting allergens, recent studies suggest that they can be directly activated by bacterial infections. In fact, in a 1999 study, scientists were able to detect mast cell activation by Borrelia burgdorferi, the spirochete that causes Lyme Disease, although they were not, at that time, able to identify the surface molecule that triggered the activation.[6]  Humans do not form an adaptive immunity to bacteria, and because all bacteria can form biofilm, there is a constant low level immune battle going on with all chronic infections. As the Mast Cells react to the bacteria they will release their contents (see table above) resulting in a continuous histamine reaction.


Known Triggers for MCAD/MCAS

If you suspect you have acquired Mast Cell Activation Syndrome (not a genetic defect) the question should be why. In addition to addressing the histamine, I believe you should also look to the root cause and treat that accordingly. The following is a partial list of known triggers for MCAD/MCAS.

1. Heavy Metals (The effects of Heavy Metal ions on histamine release)
2. Influenza Virus (Mast Cells and Influenza A Virus)
3. Parasitic Infections (Generations of Mucosal Mast Cells is Stimulated by Helminth)
4. Tuberculosis (Mycoplasma pneumonia - induced activation and cytokine production in Mast Cells)
5. Candida (Opportunistic Candida albicans elicits a temporal response in Mast Cells)
6. Fungal Infections (Role and Relevance of Mast Cells in Fungal Infections)
7. Epstein-Barr Virus (Computational discovery of Epstein-Barr Virus Targeted Genes and Pathways)
8. Lyme Disease (referenced #6 below)


What is Mastocytosis

Mastocytosis is caused by an over production of Mast Cells. These Mast Cells are also over active, in which they too easily release their contents. There are two basic types of Mastocytosis: Cutaneous (limited to skin), and Systemic (spread throughout the body), with several subtypes of each. (See AAAA&I Definition) With Mastocytosis excess mast cells build up in your skin, around blood vessels, within the respiratory system, gastrointestinal and urinary tracts or within the reproductive organs.

Conditions Associated with Mastocytosis

*Rheumatoid Arthritis
*Lupus
*Crohns Disease
*Ehlers-Danlos Syndrome
*Urticaria Pigments (cutaneous)

What Is Mast Cell Activation Syndrome (MCAS) 

Mast Cell Activation Syndrome (MCAS) is caused by over active Mast Cells without an abnormal increase in the numbers of mast cells as seen in Mastocytosis. MCAS can be a result of genetics, or triggered by stress, sunlight, bacteria, mold, viruses, allergens, drugs, and chemicals. MCAS is often found in patients with Ehlers-Dalos syndrome (EDS) and postural othrostatic tachycardia syndrome (POTS)[7]. It is also found in a subset of patients with common variable immunodeficiency (CVID) and Lyme Disease. [8]

To quote Dr. Theoharides (AKA- "The Mast Cell Master")
"Mast cells are the 'universal alarm cell" that starts the inflammatory cascade. They can be triggered by infection, allergens, environmental factors like pollution, or even emotional stress. Once that happens, mast cells set into motion a series of inflammatory reactions, including the activation of immune cells and the release of tumor necrosis factor-alpha (TNF-a), a pro inflammatory protein or cytokine." 


Common Symptoms Associated with Mast Cell Activation Syndrome

*Abdominal Pain
*Anaphylaxis
*Bloating
*Bone Pain
*Brain Fog (difficulty concentrating)
*Fatigue
*Flushing
*Food Intolerance
*Headaches
*Insomnia
*Mood swings
*Lightheadedness
*Nausea/vomiting
*Panic attacks
*Sensitivity to Multiple medications
*Shortness of Breath
*Skeletal lesions
*Skin Rashes
*Rapid Heart Rate

Common Conditions Associated with Mast Cell Activation Syndrome 

*Acne
*Allergies
*Angioedema
*Anxiety
*Asthma
*Chronic Fatigue Syndrome
*Chronic pelvic Pain
*Dermatitis
*Depression
*Dysautonomia
*Eosinophil esophagitis
*Fibromyalgia
*Gastroesophageal reflux disorder (GERD)
*Gluten Intolerance
*Interstitial cystitis (bladder pain syndrome)
*Irritable bowel syndrome
*Migraines
*Multiple chemical sensitivity syndrome
*Osteopenia
*Postural orthostatic tachycardia syndrome (POTS)

What is Histamine Intolerance

Histamine intolerance is suspected when a person has numerous adverse allergy-like reactions to foods, beverages, medications and other substances; yet shows negative results with allergy testing. The histamine intolerance is caused by histamine overload and/or diamine oxidase (DAO) deficiency. Diamine oxidase is the main histamine degrading enzyme with predominant activity in the gut. The clinical evidence for histamine intolerance is based on chronic headache, diarrhea, vomiting, heat flush, rhinitis and asthma-like symptoms.[9]


What To Do If You Suspect A Mast Cell Activation Disorder

I corresponded with Lawrence Afrin, MD a Professor of Medicine, Division of Hematology, Oncology and Transplantation at The University of Minnesota. Since the mid 2000's Dr. Afrin's clinical work has focused on hematology and mast cell disorders (See About Dr. Afrin Here). He says prior to beginning treatment for MCAD or MCAS  it is important to have "at least a couple of points of laboratory evidence to meet current published criteria." Treated properly patients can live a normal healthy life, but like any complex illness improper treatment can exacerbate the condition. Dr. Afrin has just recently published a book entitled Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity.

To Quote Dr. Afrin,
"MCAS is a chameleon, difficult to identify for many reasons. It presents with different symptoms --which are often inflammatory or allergic in nature--to varying degrees in different places in the body." 

Recommended Diagnostic Tests For MCAD/MCAS

Mastocytosis

>Skin Biopsy
>Bone Marrow Biopsy
>Blood Work: (look for anemia, elevated histamine, low platelets (thrombocytopenia), high white count (leukocytosis), low albumin levels, or high tryptase levels, D-Dimer, Complement C3a, C4a.
>Genetic Testing (see link)

Mast Cell Activation Syndrome

>Based primarily on clinical findings
>Blood Work: Serum Tryptase (above 15g/ml), elevated Cytokines, C-Reactive Protein (CRP), Fibrinogen, Cytokine-panel + Tumor Necrotic Factor (TNF), Total IgE, Serum Diamine Oxidase (below 10K/ul), 24 hour urine for Methylhistamine (PGD2), Corticotropin (CRH), Platelet Activating Factor (PAF), Vascular Endothelia Growth Factor (VEGF), 5-HIAA. (add Catecholamines for POTS)
>Other: Stool Test* (mast cells & eosinophils), Food Allergy Testing, Allergy Skin Testing
*(GI Effects gdx.net has a very comprehensive stool test, micro biome, parasites, bacteria, etc.) 

Treatment: 

*Antihistamines H1, H2, H3, H4 (see Histamine Blockers in Table Above)
*Alpha lipoid acid
*Avoid Stress
*Bisphosponates
*Digestive Enzymes
*Flavonoid
*Hypolipidemics
*Immunomodulation (allergy desensitization, stem cell transplantation)
*Low Histamine Diet
*Mast Cell Stabilizers (Cromolyn, Ketotifen, Luteolin, Quercetin, Interferon)
*NSAIDS
*N-Acetylcysteine
*Probiotics
*Proton pump inhibitors
*Vitamin C
*Tricyclic Antidepressants (antihistaminic)

References:

Other: Basic Definitions (highlighted) from Wikipedia
All Other References: Pathophysiology Clinical Concepts of Disease Process 3rd Edition

Informative Links:

-Understanding Auto-Inflammatory Disease
-Mast Cell Activation Disease: A Concise Practical Guide for Diagnostic Workup and Therapeutic
-Mast Cell Research
-Video: Dr. Lawrence Afrin - Mast Cell Activation Syndrome
-Dr. Theo Theoharides - Mast Cell Master
-American Academy of Allergy Asthma and Immunology
-National Institutes of Health Genetic and Rare Disease Information Center
-Mast Cell Proliferative Disorders: Current View on Variants Recognized by the World Health Organization

Other Helpful Links: 

-Jennifer Story: Mast Cell Activation Syndrome, Misdiagnosed as Lyme Disease
-The Many Faces of Histamine Intolerance
-Yasmin Ykelenstam - Healing Histamine: Natural Mast Cell Stabilizers for Histamine
-Mast Cell Aware

I will leave you with this final Quote from Dr. Afrin:
You will not find another disease besides systemic mast cell disease that better illustrates the old “four blind men and an elephant” problem. There are lots of factors that go into every specialist looking at a patient with mast cell disease from a different perspective, seeing only the problems that they’ve been taught to see in their own domain. And in the first 13 years of my career post-fellowship, I practiced that way, too.
As just one example, I can’t begin to count the numbers of patients I’ve seen in that time who’ve had “anemia of chronic inflammation.” Mysterious anemia, nobody knows why, no clear source of the chronic inflammation, and we just leave it at that.
And it’s acceptable in the medical community to just leave it at that. For lots of reasons (many relating to our healthcare financing systems), the physician can’t spend nearly as much time with each patient as would be needed or desirable to get to the root of every mystery.
So the hematologist sees the anemia, the gastroenterologist sees the irritable bowel syndrome, the rheumatologist sees the fibromyalgia, the cardiologist sees the palpitations, the neurologist sees the migraine headaches and neuropathy, and so on and so forth.
We all just constantly miss the elephant.

44 comments:

  1. Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Cancer,Scoliosis,Fibromyalgia,Fluoroquinolone Toxicity
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  2. I am bold enough among many others to state that there is now a potent cure to this sickness but many are unaware of it. I discovered that I was infected with the virus 3 months ago, after a medical check-up. My doctor told me and I was shocked, confused and felt like my world has crumbled. I was dying slowly due to the announcement of my medical practitioner but he assured me that I could leave a normal life if I took my medications (as there was no medically known cure to Herpes). I went from churches to churches but soon found that my case needed urgent attention as I was growing lean due to fear of dying anytime soon. In a bid to look for a lasting solution to my predicament, I sought for solutions from the herbal world. I went online and searched for every powerful trado-medical practitioner that I could severe, cos I heard that the African Herbs had a cure to the Herpes syndrome. It was after a little time searching the web that I came across one Dr Itua(A powerful African Herbal Doctor), who offered to help me at a monetary fee. I had to comply as this was my final bus-stop to receiving a perfect healing. My last resolve was to take my life by myself, should this plan fail. At last it worked out well. He gave me some steps to follow and I meticulously carried out all his instructions. Last month, to be precise, I went back to the hospital to conduct another test and to my amazement, the results showed that negative,Dr Itua Can As Well Cure The Following Desease…Cancer,Hiv,Herpes, Hepatitis B,Liver Inflammatory,Diabetis,Fribroid,,Non Hodgkin Lymphoma,Skin Cancer,Uterine Cancer,Prostate Cancer Dercum,Infertility,fibromyalgia,Get Your Ex Back,Als,SYPHILLIS,Genetic disease,Epilepsy, Parkinson's disease..You can free yourself of this Herpes virus by consulting this great African Herbal Doctor via this e-mail: drituaherbalcenter@gmail.com or call and whatsapp him on +2348149277967 He will help you and his herb medication is sure. he has the cure on all disease .You can talk to me on INSTAGRAM..tashamoore219....

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  3. Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Cancer,Scoliosis,Fibromyalgia,Fluoroquinolone Toxicity
    Syndrome Fibrodysplasia Ossificans Progressiva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Sclerosis,Alzheimer's disease,Adrenocortical carcinoma.Asthma,Allergic diseases.Hiv_ Aids,Herpe ,Copd,Diabetes,Hepatitis,I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man.

    ReplyDelete

  4. I am bold enough among many others to state that there is now a potent cure to this sickness but many are unaware of it. I discovered that I was infected with the virus 3 months ago, after a medical check-up. My doctor told me and I was shocked, confused and felt like my world has crumbled. I was dying slowly due to the announcement of my medical practitioner but he assured me that I could leave a normal life if I took my medications (as there was no medically known cure to Herpes). I went from churches to churches but soon found that my case needed urgent attention as I was growing lean due to fear of dying anytime soon. In a bid to look for a lasting solution to my predicament, I sought for solutions from the herbal world. I went online and searched for every powerful trado-medical practitioner that I could severe, cos I heard that the African Herbs had a cure to the Herpes syndrome. It was after a little time searching the web that I came across one Dr Itua(A powerful African Herbal Doctor), who offered to help me at a monetary fee. I had to comply as this was my final bus-stop to receiving a perfect healing. My last resolve was to take my life by myself, should this plan fail. At last it worked out well. He gave me some steps to follow and I meticulously carried out all his instructions. Last month, to be precise, I went back to the hospital to conduct another test and to my amazement, the results showed that negative,Dr Itua Can As Well Cure The Following Desease…Cancer,Hiv,Herpes,Shingles, Hepatitis B,Liver Inflammatory,Diabetis,Fribroid,Parkinson's,Alzheimer’s disease,Bechet’s disease,Crohn’s disease
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    Syndrome Fibrodysplasia Ossificans ProgresSclerosis,Seizures,Adrenocortical carcinoma.Asthma,Allergic diseases,,Copd,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.
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    Replies
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    Love Spell,Diabetes.

    ReplyDelete
  7. There is a safe & effective Natural Herbal Medicine. For Total Cure Call    +2349010754824,  or email him   drrealakhigbe@gmail.com       For an Appointment with (Dr.) AKHIGBE contact him. Treatment with Natural Herbal Cure. For:Dengue Fever, Malaria. Painful or Irregular Menstruation. HIV/Aids. Diabetics. Vaginal Infections. Vaginal Discharge. Itching Of the Private Part. Breast Infection. Discharge from Breast. Breast Pain & Itching. Lower Abdominal Pain. No Periods or Periods Suddenly Stop. Women Sexual Problems. High Blood Pressure Chronic Disease. Pain during Sex inside the Pelvis. Pain during Urination. Pelvic Inflammatory Disease, (PID). Dripping Of Sperm from the Vagina As Well As for Low sperm count. Parkinson disease. Obesity, Lupus.  Cancer.  Tuberculosis.  Zero sperm count. Bacteria Diarrhea.Herpatitis A&B, Rabies. Asthma.  Quick Ejaculation. Gallstone, Esquizofrenia, Cirrhosis,  Premature Ejaculation. Herpes. Joint Pain. Stroke. Coeliac Disease, Weak Erection.  Erysipelas, Thyroid, Discharge from Penis. HPV.  Hepatitis A and B. STD. Staphylococcus + Gonorrhea + Syphilis. Heart Disease.  Pile-Hemorrhoid.rheumatism, thyroid, Autism, Penis enlargement,  Waist & Back Pain.  Male Infertility and Female Infertility. Etc. Take Action Now. contact him & Order for your Natural Herbal Medicine:  +2349010754824  and email him    drrealakhigbe@gmail.com    Note For an Appointment with (Dr.) AKHIGBE.I suffered in Cancer for a year and three months dieing in pain and full of heart break. One day I was searching through the internet and I came across a testimony herpes cure by doctor Akhigbe. So I contact him to try my luck, we talk and he send me the medicine through courier service and with instructions on how to be drinking it.To my greatest surprise drinking the herbal medicine within three weeks I got the changes and I was cure totally. I don't really know how it happen but there is power in Dr Akhigbe herbal medicine. He is a good herbalist doctor.

    ReplyDelete
  8. My sister was diagnosed of Creutzfeldt–Jakob disease (CJD) in early last year , our doctor told us there is no permanent cure for the CJD condition, she was given medications to slow down the progress of the disease, at the initial stage it was not so bad till it progressed to the end stage were she had difficulties going about her daily functions as she constantly had difficulty speaking,mental confusion,blurred vision include, we were all totally devastated not until my daughter’s co-worker told us about a herbal formula from totalcureherbsfoundation .com which has the right herbal formula for my sister Creutzfeldt–Jakob disease , when I contact this herbal foundation through their email totalcureherbalfoundation@ gmail. com I wasn’t certain the herbal treatment will get rid of herbal disease not until she complete the treatment as instructed, she will be resuming her work next month because this herbal cure seriously reverse her condition which we never expected ,im referring this to anybody at there suffering from this condition and they have assurance about this treatments

    ReplyDelete
  9. Good day brothers and sister. i am here to share a testimony of what God Almighty has done for me by using Dr Ogbeifun to cure me permanently from diabetes type 2. i have try different medication, injection and there wasn't a solution, even order natural herbs from other doctors before i came across Dr Ogbeifun. i am living happily today with my family?i will want those who is affected with diseases,virus,infections don't loss hope there is a cure to get rid of Herpes
    Cancer
    Lupus
    ALS
    Arthritis
    HIV
    Hepatitis A,B,C
    Shingles
    Diabetes
    Asthma ETC.
    Get in touch with Dr Ogbeifun WhataApp +2348050680253
    Email address: drogbeifunherbalhome1@gmail.com
    Website: https://drogbeifunherbalho1.wixsite.com/drogbeifunherbalhome

    ReplyDelete
  10. I saw the fear in my husband and children's eyes when I told them about my condition then they start to find solution on their own to help my condition.I am an 59 now who was diagnose COPD emphysema which I know was from my years of smoking. I started smoking in school when smoking was socially acceptable. I remember when smoking was permitted in hospitals. It was not known then how dangerous cigarettes were for us, and it seemed everybody smoked but i was able to get rid of my COPD lung condition through the help of total cure herbal foundation my husband bought, totalcureherbsfoundation .c om has the right herbal formula to help you get rid and repair any lung conditions and cure you totally with their natural organic herbs. I wish anybody who starts smoking at a young age would realize what will eventually happen to their bodies if they continue that vile habit throughout their life.

    ReplyDelete
  11. I am here to give my testimony about Dr Ebhota who helped me.. i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by salami, i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Dr Ehbota cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took for just 2 weeks and it seriously worked for me, my HERPES result came out negative. I am so happy as i am sharing this testimony. My advice to you all who thinks that there is no cure for herpes that is Not true just contact him and get cure from Dr Ebhota healing herbal cure of all kinds of sickness you may have like
    (1) CANCER,
    (2) DIABETES,
    (3) HIV&AIDS,
    (4) URINARY TRACT INFECTION,
    (5) CANCER,
    (6) IMPOTENCE,
    (7) BARENESS/INFERTILITY
    (8) DIARRHEA
    (9) ASTHMA
    (10)SIMPLEX HERPES AND GENITAL
    (11)COLD SORE
    HERPES. he also cure my friend from cervical cancer Email: drebhotasoultion@gmail.com or whatsapp him on +2348089535482

    ReplyDelete
  12. Lets join hands together and eradicate HIV and HERPES from this planet earth. Anybody who still think there is no cure for hiv or herpes should deviate from it because a cure has been found by Dr Ehijator. He uses herbs to cure these diseases. I am a living testimony of Dr Ehijator, he use his herbal medicine to cure me from HIV and HERPES. I was infected with two difference diseases HIV and HERPES VIRUS which cost me my relationship and i could not bear the pains of living with the disease and loosing my boyfriend. So i went in search of getting the cure and i saw a comment on YouTube on how Dr Ehijator uses his herbs to cure people of HIV and other diseases. I quickly contact him on the email that was present on the comment and told him about my illness and he prepare my medicine and send it to me through UPS service and he gave me instructions on how to take it and after i finish taking the herbs,i went to the hospital for checkup and behold the test shows that am HIV and HERPES negative. The doctors at the hospital rejoice with me and ask for Dr Ehijator contact. If you are in need of help to get the cure from Dr Ehijator, you can contact him on email: drehijatorherbalcenter@gmail.com or you can whatsapp him on +2349039447158
    Dr Ehijator Can Also Cure The Fellowing Diseases.
    1 Cancer of all kind
    2 Hiv/aids
    3 HSV1&2
    4 Barrenness
    5 Hpv
    6 Herpes
    7 Genital Wart
    8 Rare disease
    9 Hepatitis
    10 Cold Sore
    11 ALS
    12 firbord
    13 penis enlargement
    14 all kinds of sicknesss
    15 Love spell
    16 diabetes

    ReplyDelete
  13. Greetings to you all, i am here today for my family life testimony on how I was cured from HPV while this may sound discouraging and people may not believe that HPV &HIV CURE has be found, while i was once an HIV i live with this disease for more than a year now, i have been to so many places for help including hospitals wasted money and times hoping that i was going to get cure but non was able, until God use someone to cure me from this disease HPV true the help of a man called Dr EBHOTA with his herbal root herbs medicine. while i don’t have much to say but to give thanks and praise to God almighty who use Dr Ebhota to extend my life for what you have done for me DR, i will not stop thanking you because you put a smile on my face again. thanks once again if you are into similar problem or with any kind of diseases you can contact Sir Dr EBHOTA call him on +2348089535482 or WhatsApp and i will not stop thanking you Dr EBHOTA . for what you have done for me in my life, i will keep posting to the world for them to know that you are in existence, thanks for your audience and i hope you find help like i did for what he has done for me, if you are into similar problem like...
    1. BREAST CANCER
    2. HERPES A&B
    3. SPINE DISORDER
    4. CANCER
    5. HEPATITIS AB&C
    6. DIABETES
    7. HIV

    :: whatsapp him on this +2348089535482 or inbox him on drebhotasolutoin@gmail.com God will bless you Sir for the work of my family.,,,,,,,,,,,,,,,,,, 

    ReplyDelete
  14. I'm so exited to share my testimonies about the Good Work of Dr. Udebhu who get me cured from herpes simplex virus (HSV1&2) with his herbs, I never thought that I will live on earth before the year runs out. I have been suffering from herpes, I had spent a lot of money going from one Hospital to another looking for way to get rid of this disease, the hospital have been my home everyday residence. Constant checks up have been my hobby not until this faithful day, I was searching
     through the internet, I saw a testimony on how Dr.Udebhu helped someone in curing his herpes disease using his healing
     Herbs, quickly I copied his email just to give him a test I spoke to him, he told me that he is going to provide the herbal cure to me, which he
    did, after i receive his herbs and i take it as instructed i was cure permanently from herpes my herpes disease was gone. so I decided to share my testimony, that nothing is impossible with God, God use a man to healed me. No matter what you are passing through, no matter how deadly the sickness is and no matter what the situation is God that did mine is still going to do yours, people suffering from herpes, brain tumor, kidney disease, pcos, AIDS, ALS,copd, asthma, athritis,herpes, Cancer,Hpv, any kind of disease, you can rich him now via ? Gmail address: drudebhuherbalhome@gmail.com or whatsapp +2349051254152  

    ReplyDelete
  15. HIV is a terrible disease, if not for my wife and the help of the great Dr. Apala my life would have been a mess! I was diagnosed with HIV in 2005, my wife encouraged me, and told me not to lose hope, we manage to give birth to a baby Boy who was free from the disease, and my wife was always there for me! One day she came to me and told me that he have found a man who can cure me. Base on scientist, they said there is no cure for HIV; he told me that he has seen many testimonies about him on the internet. We decided to contact him ask me some question about myself and the diease , and he asked us to buy his herbal cure that is goimg to help me which we did! 14 days later he asked me to go for HIV test, faithfully I went to do the Test, Lo and Behold, I was cured, the virus was not found in my Body... My Dear wife and my Father Dr. Apala God will surely bless the both of you, till the end of time, in Jesus name.. If you have any problem kindly contact he on (dr.apalaherbalhome@gmail.com) call or whatsapp him on +2348114047176
    he also special on cureing
    1. HIV/AIDS

    2. HERPES
    3. CANCER
    4. ALS
    5. HEPATITIS B
    6.
    DIABETES
    7. HUMAN PAPILOMA VIRUS DISEASE(HPV)

    8. ALZHEIMER
    9. LUPUS (Lupus Vulgaris or Lupus
    Erythematosus)

    ReplyDelete
  16. WHAT A GREAT MIRACLE THAT I HAVE EVER SEE IN MY LIFE. My names are Clara David I’m a citizen of USA, My younger sister was sicking of
    breast cancer and her name is Sandra David I and my family have taking her
    to all kind of hospital in USA still yet no good result. I decided to go to
    the internet and search for cancer cure so that was how I find a lady
    called peter Lizzy she was testifies to the world about the goodness of a
    herbal man who has the roots and herbs to cure all kind of disease and the
    herbal man email was there. So I decided to contact the herbal man @herbalist_sakura for my younger sister help to cure her breast cancer. I contacted him and told him
    my problem he told me that I should not worry that my sister cancer will be
    cure, he told me that there is a medicine that he is going to give me that
    I will cook it and give it to my sister to drink for one week, so I ask how
    can I receive the cure that I am in USA, he told me
    That I will pay for the delivery service. The courier service can
    transport it to me so he told me the amount I will pay, so my dad paid for
    the delivery fee. two days later I receive the cure from the courier
    service so I used it as the herbal man instructed me to, before the week
    complete my sister cancer was healed and it was like a dream to me not
    knowing that it was physical I and my family were very happy about the
    miracle of Doctor so my dad wanted to pay him 5 million us dollars the
    herbal man did not accept the offer from my dad, but I don't know why he
    didn't accept the offer, he only say that I should tell the world about him
    and his miracle he perform so am now here to tell the world about him if
    you or your relative is having any kind of disease that you can't get from
    the hospital please contact dr.sakuraspellalter@gmail.com or whats app him
    +2348110114739  you can follow him up on Instagram @herbalist_sakura for the cure, he will help you out with the
    problem. And if you need more information about the doctor you can mail me
    davidclara223@gmail.com 

    ReplyDelete
  17. I am 58 years old, and was diagnosed with heart failure over a year ago. My main symptoms was fatigue, shortness of breath, and a general sense that these symptoms will keep me out of normal life activities, my symptom was not being able to breathe when lying down basically . I’ve kind of resigned to the fact that this is how life will be for me back until I found herbs that stop this CHF easily and relief all the airways. My wife and her caregiver assume I can't be as active, and thus I was excused from normal life responsibilities but natural herbs from totalcureherbsfoundation. com really helped a but sometimes I think is God prodigy that I was able to treat my congestive heart failure  but total cure herbs foundation herbal formula has a big impact on my recovery because my heart condition has been fully eliminate. They do things for me, and was too happy to comply with their service. This is a equitable of a way to get of your heart failure.

    ReplyDelete
  18. Good-day viewers that is reading this article, i want to share to the world how this great man save me from HERPES VIRUS 1/2 3years back i was battling with this terrible and disastrous disease which was so detesting,well on my aid of looking for solution all my effort conceived nothing, I was devastated but one day out of great enthusiasm i saw this intrigue testimonies about Dr Itohan so afterwards i contacted Dr Itohan on his emails: (greatcureman@gmail com) I explained myself to him and i obeyed all his instruction without protesting any further he assured me that all will be fine and that was it,i was totally cure when i used the herbal medicine that was sent to me,Thank so much sir Dr Itohan for your help, Dr Itohan also cures several diseases such as EBV,VAGINITIS, LOW SPERM COUNT, ALL KIND OF STDS, HIV AIDS, HEPATITIS B & C, DIABETES,CANCERS  And many more diseases, incase you are going through this same infections don't hesitate to contact him right  now and get cured.He's a good man and can also advice you on how to handle your marital issues thanks
    reach his mobile or  whatsapp Him on +2348152855846
    E-mail    greatcureman@gmail.com

    ReplyDelete
  19. I'm here to give my testimony how I was cured from HIV, I contacted my HIV via blade. A friend of my use blade to peel of her finger nails and drop it where she use it, so after she has left i did know what came unto me i looked at my nails, my nails were very long and I took the blade which she just used on her own nails to cut of my finger nails, as i was maintaining my names, i mistakenly injured myself. I did even bother about it, so when I got to the hospital the next week when i was ill the doctor told me that I am HIV positive, i wondered where did i got it from so i remembered how I use my friend blade to cut off my hand so i feel so sad in my heart to the extent that i don’t even know what to do, so one day i was passing through the internet i met a testimony of a lady that all talk about how she was cured by a doctor called DR Imoloa so i quickly emailed the doctor and he also replied to me and told me the requirements which i will provide and I do according to his command, he prepare a herbal medicine for me which I took. He message me the following week that i should go for a test which i did to my own surprise i found that i was HIV negative. He also have cured for all kinds of incurable diseases like: Huntington's disease, back acne, chronic kidney failure, Addison's disease, Chronic Disease, Crohn's Disease, Cystic Fibrosis, Fibromyalgia, Inflammatory Bowel Disease, Fungal Nail Disease, Paralysis, Celia Disease , Lymphoma, Major Depression, Malignant Melanoma, Mania, Melorheostosis, Meniere's Disease, Mucopolysaccharidosis, Multiple Sclerosis, Muscle Dystrophy, Rheumatoid Arthritis, Alzheimer Disease and so many. Thanks to him once more the great doctor that cured me dr. Imoloa so you can also email him via drimolaherbalmademedicine@gmail.com or what'sapp him on +2347081986098.. God Bless you Sir.

    ReplyDelete
  20. cigarette smoking is the number one risk factor for lung cancer,cigarette smoking is linked to about 80% to 90% of lung cancer deaths. Lung cancer is the most common form of the disease in the world and 90 percent of all cases are caused by cigarette smoking. About 10 to 15 percent of smokers develop lung cancer — although they often die of other smoking-related causes like heart disease, stroke or emphysema. lung cancer often goes unnoticed in its early stages. As the disease develops, a persistent cough  develop and chronic cough worsen. including chest pain, shortness of breath, hoarseness, bloody fluid coughed up from the respiratory tract, and frequent bouts of bronchitis or pneumonia. Sometimes all your bones begin pains or hurts you so bad, headaches, dizziness,I was so pissed off and tired of my life,after I developed lung cancer from cigarette smoking and I was at the point of death,through my boredom I was surfing the internet then  I came across re Dr James herbal mix. who said he can cure lung cancer with his herbal mix and got herbal cleansers from smoking too.I really thought it was a joke until I have gotta try. when I contacted him,he said yes he can. so little time I thought  about it and bought the herbal medicine which I took couple of week to get to me.within one week of taken it I started seeing  a lots of changes till  I was totally cured. his treatment is so unique,I never thought i will be able to be free from Lung Cancer and smoking treat too.He saved my life and I'm strong and healthy right now.You can speak with Him direct on his mobile/whatsapp  +2348152855846
    E-mail  drjamesherbalmix@gmail.com

    ReplyDelete
  21. HOW I GOT CURED OF HERPES DISEASE
    I'm here to testify about what DR. OSO did for me. I have been suffering from (HERPES) disease for the past 5 years and had constant pain,especially inside my body. During the first year,I had faith in God that i would be healed someday. This disease started circulating all over my body and i have been taking treatment from my doctor, few weeks ago i came across a testimony of one lady on the internet testifying about a Man called DR. OSO on how he cured her from herpes disease. And she also gave the email address of this man and advise anybody to contact him for help for any kind of sickness that he would be of help.so I emailed him telling him about my (HERPES) he told me not to worry that i was going to be cured!! Well i never believed it,, well after all the procedures and remedy given to me by this man few weeks later i started experiencing changes all over me as DR. OSO assured me that i will be cured,after some time. i went to my doctor to confirmed if i have be finally healed behold it was TRUE,the test came out negative. So friends my advise is if you have such sickness or any other at all you can contact DR. OSO for help.
    Email} drosohaberhome@gmail.com 

    WhatsApp /call +2348162084839   

    https://sites.google.com/view/drosohaberhome/

    His blog pagehttps://drosohaberhome.blogspot.com  

      https://www.facebook.com/drosoherbalhome/ 
     
    you can also email me for more information about DR oso via smithmorgan2777@gmail.com ALL THANK TO DR OSO .  

    ReplyDelete
  22. I was suffering from chronic hepatitis B , I spent alot on drugs, i never thought that a day like this will come and i will be able to give up on drugs. i found dr_anuge contact on blog when someone talked about DR ANUGE, so i contacted him via email: dranuge@gmail.com and made purchase of the hepatitis Vaccine, i received his herbal medicine through UPS delivery service within 3 days, when i received the medicine i applied it as prescribed and i was totally cured of hepatitis b within few's weeks of usages, i went back to my doctor and he confirmed i was free curable cured from the disease, am so happy now living a normal life again thanks to Dr_Anuge Viewers contact Him via email: dranuge@gmail.com Or you can also reach him via WhatsApp +2348164866838 He's also specialized in the following:HIV /AIDS CURE
     HEPATITIS CURE 
    DIABETES CURE
    STROKE 
    HERPES SIMPLEX CURE
    EPILEPSY
     CANCER CURE
     FIBROID
     HIGH BLOOD PRESSURE 
    HERBAL MEDICINE FOR PREGNANCY
     LOVE SPELL AND MONEY SPELL...

    ReplyDelete
  23. Never give up in life they all say no cure to HSV 2 which is a big lie I have pass through many process also i never believe there is really cure to HERPES until I meet Dr.Emmanuel the doctor that have been helping many people for many years, I come across this doctor online when I was searching for cure online I found out about this man, and to my greatest surprise this man have the herbal medicine which I have been looking for years I explain my problem to him through the email I found on someone who testify about him also, Dr.Emmanuel write me a reply and explain how the process work so after ordering for the medicine I got it within 4 days and I took it according to the way Dr.Emmanuel instructed, I was so happy after two week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative that was the day I have the tears of joy you can also get in contact with my doctor through his email now nativehealthclinic@gmail.com or you can also WhatsApp him +2348140073965. And He a lso have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC 

    ReplyDelete
  24. Never give up in life they all say no cure to HSV 2 which is a big lie I have pass through many process also i never believe there is really cure to HERPES until I meet Dr.Emmanuel the doctor that have been helping many people for many years, I come across this doctor online when I was searching for cure online I found out about this man, and to my greatest surprise this man have the herbal medicine which I have been looking for years I explain my problem to him through the email I found on someone who testify about him also, Dr.Emmanuel write me a reply and explain how the process work so after ordering for the medicine I got it within 4 days and I took it according to the way Dr.Emmanuel instructed, I was so happy after two week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative that was the day I have the tears of joy you can also get in contact with my doctor through his email now nativehealthclinic@gmail.com or you can also WhatsApp him +2348140073965. And He a lso have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC 

    ReplyDelete
  25. I never thought that i will ever have a normal life again thinking I'll never get out of this hiv virus in my whole life but i was wrong. My story goes thus: I found dr tokubo contact in a post i followed online, I copied the email and contacted him because i read about how he cure a man of hiv and that he have herbal remedy for cancer, yeast infection,HIV, Herpes e.t.c. I told him all he needed to know about my hiv status and he told me to relax and stay calm that he will help me by sending his medicine to me via courier delivery and he did as he promised. I received my healing within 10 days of using his herbal remedy. my lost joy came back alive as there is no more HIV, no symptoms, no fear of transmitting the virus to my love ones. Now I'm in a relationship and my sex life is awesome. All these happened last month ago and I decided to keep silent because I wanted to be sure of the healing. Now I'm saying this because I have undergone series of medical check up and all results came out negative. At first i thought it was just a joke until i tried it out and it worked perfectly well. The doctor never asked me to talk about him but I see it as my little way of showing other people out there need his herbal medicine to be cured.  You can reach dr tokubo via his email at: drtokubotemple@gmail.com or you can whatsapp him on: +2349037990322

    ReplyDelete
  26. I am here to give my testimony about Dr Anuge who helped me.. i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by Dr Anuge, i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Dr anuge cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took for just 2 weeks and it seriously worked for me, my HERPES result came out negative. I am so happy as i am sharing this testimony. My advice to you all who thinks that there is no cure for herpes that is Not true just contact him and get cure from Dr Anuge healing herbal cure of all kinds of sickness you may have like
    (1) CANCER,
    (2) DIABETES,
    (3) HIV&AIDS,
    (4) URINARY TRACT INFECTION,
    (5) CANCER,
    (6) IMPOTENCE,
    (7) BARENESS/INFERTILITY
    (8) DIARRHEA
    (9) ASTHMA
    (10)SIMPLEX HERPES AND GENITAL
    (11)COLD SORE
    and mare that are not mentioned here
    . he also cure my friend from cervical cancer. so contact him thruogh his Email address : dranuge@gmail.com or whatsapp him on +234816466838 here is also his IG link @Dr_Anuge7 for more information ........

    ReplyDelete
  27. I'm so excited to share my testimonies about the Good Work of  Dr. Anuge who got me cured from herpes simplex virus (HSV1&2) with his herbs, I never thought that I would live on earth before the year runs out. I have been suffering from herpes, I had spent a lot of money going from one Hospital to another looking for a way to get rid of this disease, the hospital has been my home everyday residence. Constant checks up have been my hobby not until this fateful day, I was searching through the internet, I saw a testimony on how @Dr_anuge7 helped someone in curing his herpes disease using his healing Herbs, quickly I copied his email just to give him a test I spoke to him, he told me that he is going to provide the herbal cure to me, which he did, after I received his herbs and I took it as instructed. I was cured permanently from herpes. My herpes disease was gone. so I decided to share my testimony, that nothing is impossible with God, God used a man to heal me. No matter what you are passing through, no matter how deadly the sickness is and no matter what the situation is God that did mine is still going to do yours, people suffering from herpes, brain tumor, kidney disease, pcos, AIDS, ALS,copd, asthma, arthritis,herpes, Cancer,Hpv, any kind of disease, you can reach him now via ? Gmail address: dranuge@gmail.com or whatsapp  +2348164866838

    ReplyDelete
  28. I'm so excited to share my testimonies about the Good Work of  Dr. Anuge who got me cured from herpes simplex virus (HSV1&2) with his herbs, I never thought that I would live on earth before the year runs out. I have been suffering from herpes, I had spent a lot of money going from one Hospital to another looking for a way to get rid of this disease, the hospital has been my home everyday residence. Constant checks up have been my hobby not until this fateful day, I was searching through the internet, I saw a testimony on how @Dr_anuge7 helped someone in curing his herpes disease using his healing Herbs, quickly I copied his email just to give him a test I spoke to him, he told me that he is going to provide the herbal cure to me, which he did, after I received his herbs and I took it as instructed. I was cured permanently from herpes. My herpes disease was gone. so I decided to share my testimony, that nothing is impossible with God, God used a man to heal me. No matter what you are passing through, no matter how deadly the sickness is and no matter what the situation is God that did mine is still going to do yours, people suffering from herpes, brain tumor, kidney disease, pcos, AIDS, ALS,copd, asthma, arthritis,herpes, Cancer,Hpv, any kind of disease, you can reach him now via ? Gmail address: dranuge@gmail.com or whatsapp  +2348164866838

    ReplyDelete
  29. I am glad to confirm that this herbal medicine really works as my last result was negative ...i used it for a week. Were you told hiv or other STD or STI doesn't have a cure? worry no more because i have good news for you. If you are in need of hiv, herpes or any other kind of STD or STI cure kindly search for this name in the bracket as follow: (( Dr Tokubo Temple )) Search for the dr name on google search or youtube you will find his page there.

    ReplyDelete
  30. I am here to express my profound warm gratitude to the herbal medicine, which I got from Dr. Imoloa. I am now living a healthy life since the past 6 months. I am now a genital herpes virus free after the herbal medication I got from him. You can contact him for your medication Via his email- drimolaherbalmademedicine@gmail.com/ whatsapp +2347081986098/ website www.drimolaherbalmademedicine.wordpress.com

    ReplyDelete
  31. There are some natural remedies that can be used in the prevention and eliminate diabetes totally. However, the single most important aspect of a diabetes control plan is adopting a wholesome life style Inner Peace, Nutritious and Healthy Diet, and Regular Physical Exercise. A state of inner peace and self-contentment is essential to enjoying a good physical health and overall well-being. The inner peace and self contentment is a just a state of mind.People with diabetes diseases often use complementary and alternative medicine. I diagnosed diabetes in 2010. Was at work feeling unusually tired and sleepy. I borrowed a cyclometer from a co-worker and tested at 760. Went immediately to my doctor and he gave me prescriptions like: Insulin ,Sulfonamides,Thiazolidinediones but Could not get the cure rather to reduce the pain but bring back the pain again. i found a woman testimony name Comfort online how Dr Akhigbe cure her HIV  and I also contacted the doctor and after I took his medication as instructed, I am now completely free from diabetes by doctor Akhigbe herbal medicine.So diabetes patients reading this testimony to contact his email     drrealakhigbe@gmail.com   or his Number   +2348142454860   He also use his herbal herbs to diseases like:SPIDER BITE, SCHIZOPHRENIA, LUPUS,EXTERNAL INFECTION, COMMON COLD, JOINT PAIN, EPILEPSY,STROKE,TUBERCULOSIS ,STOMACH DISEASE. ECZEMA, PROGENITOR, EATING DISORDER, LOWER RESPIRATORY INFECTION,  DIABETICS,HERPES,HIV/AIDS, ;ALS,  CANCER , MENINGITIS,HEPATITIS A AND B,ASTHMA, HEART DISEASE, CHRONIC DISEASE. NAUSEA VOMITING OR DIARRHEA,KIDNEY DISEASE. HEARING  LOSSDr Akhigbe is a good man and he heal anybody that comes to him. here is email    drrealakhigbe@gmail.com    and his Number +2349010754824

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  32. Herbal medication will remain the only best way to get rid of many diseases and viruses that are said to have no cure by scientist doctors. AM HERE TO CONFIRM TO YOU ALL ON HOW I GOT CURED OF HIV  VIRUS! Who will believe that herbs can cure hiv? i never believe that this will work, i have spent a lot getting drugs from the hospital to keep me healthy, it got to a point that all i was waiting for is death to come because i was broke, one day i heard about this great man called DR TOKUBO who is well know for curing Cancer, Diabetes, HIV, Fibroid,Hepatitis b, HSV, HPV And Herpes cure. I decided to contact him, I didn't believe him that much, I just wanted to give him a try, he replied my mail and needed some Information about me, then I sent them to him, he prepared a herbal medicines and sent it through Courier Service for delivery, he gave my details to the Courier Office, they told me that 2-3 days i will receive the package and after receiving it, i took the medicine as prescribed by him, after finishing the medicine, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me HIV virus negative, i thought it was a joke, i went to other hospital and the result also came out negative, Ever since then i promise myself to testify on the internet so that other positive victims out there can reach dr tokubo for cure.  if you are HIV virus or above listed diseases/infection positive, contact dr tokubo and I assure you that you will absolutely get cured.
    His EMAIL(drtokubotemple@gmail.com)
    You can call or add him up on WhatsApp(+2349037990322)

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  33. Herbal medication will remain the only best way to get rid of many diseases and viruses that are said to have no cure by scientist doctors. AM HERE TO CONFIRM TO YOU ALL ON HOW I GOT CURED OF HIV  VIRUS! Who will believe that herbs can cure hiv? i never believe that this will work, i have spent a lot getting drugs from the hospital to keep me healthy, it got to a point that all i was waiting for is death to come because i was broke, one day i heard about this great man called DR TOKUBO who is well know for curing Cancer, Diabetes, HIV, Fibroid,Hepatitis b, HSV, HPV And Herpes cure. I decided to contact him, I didn't believe him that much, I just wanted to give him a try, he replied my mail and needed some Information about me, then I sent them to him, he prepared a herbal medicines and sent it through Courier Service for delivery, he gave my details to the Courier Office, they told me that 2-3 days i will receive the package and after receiving it, i took the medicine as prescribed by him, after finishing the medicine, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me HIV virus negative, i thought it was a joke, i went to other hospital and the result also came out negative, Ever since then i promise myself to testify on the internet so that other positive victims out there can reach dr tokubo for cure.  if you are HIV virus or above listed diseases/infection positive, contact dr tokubo and I assure you that you will absolutely get cured.
    His EMAIL(drtokubotemple@gmail.com)
    You can call or add him up on WhatsApp(+2349037990322)

    ReplyDelete
  34. FINALLY FREE FROM HERPES VIRUS. what a miracle i never believe there is cure because my doctor tested me herpes positive and she told me there is no cure, i’m very happy today that i’m having a free life without this herpes virus, i can remember some months ago when i was crying all through the night and day that i can’t get cured from this herpes, i found this herbal man called Dr Adigba on internet when i was doing research on cure for shingle i contacted him to found out if i can get help from this herpes virus, i was so surprise when he told me that he have the herbs cure to it and he sent me the herbal in less down 5 days i was so happy when i get someone giving me hope that he can cured me i took the herbal for just 2 weeks, when i went for test after taking the herbal i found out that i am cured i was so happy and surprise, i want to use this opportunity to inform you that there is cured to herpes virus you can also contact him for his help as soon as possible so that you can get rid of this herpes once and for all you can reach him through this email: dradigba@gmail.com or whatsApp him on +2348077875210 You can also contact him on any disease and virus in this he all have the herbal cure to it. 1 HIV/AIDS 2 HERPES 3 CANCER 4 ALS 5 HEPATITIS 6 DIABETES 7 LOVE SPELL 8 INFECTIONS 9 HIGN BLOOD PRESSURE,..... THANKS TO DR SUNNYNA FOE THE GOOD WORK IN LIFE YOU BLESS.....

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  35. THANKS TO DR OSAZE WHO CURERD ME OF STAPHYLOCOCUS INFECTION, I WAS INFECTED WITH STAPH FOR OVER FIVE YEARS, I VISITED SEVERAL HOSPITAL AND BOUGHT ALL KINDS OF ANTIBIOTICS FOR TREATMENT, ALL TO NO AND VAIL, NTIL SOMEONE RECOMMENDED ME TO DR OSAZE HERBAL HOME, AND HE ADMINISTERED HIS HERBAL MEDICATION ON ME, AND I WAS CURED WITHIN A MONTHAND A WEEK.
    IN CASE YOU ARE FACING SUCH PROBLEM, AND YOU NEEDS DR OSAZE ASSISTANCE, YOU CAN CALL OR WHATSAP HIM ON +2347089275769 OR EMAIL DROSAZE39@GMAIL.COM

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  36. Here is  my testimony on how I was cured of HIV by Dr Akhigbe,with his natural herbal medicine.  on a regular basis in efforts to help others when I could. As you may know, each donation is tested.  Well, on July 6th I had a meeting with a Red Cross representative and was told that I had HIV. “What went through your mind when you heard that "Rose" Good question reader! To be honest, I thought my life was over, that I would ever find love, get married, have children or anything normal. Lucky for me I have an amazing support system.  My family supported me then I never thought that I was invincible to STD s or pregnancy or anything else parents warn their kids about. I just didn’t think about it. I was in a monogamous relationship and thought that I asked the right questions.  We even talked about marriage Scary.  During that time I was in college and donated blood on a re as well. who helped me in search of cure through the media.there we saw a good testimony of sister 'Kate' about the good work of Dr Akhigbe natural herbal medicine cure.then I copied his email address and contacted him. A good herbalist doctor with a good heart, he is kind, loving and caring. He replied back to my message and told me what to do. After a week the doctor sent me my herbal medicine and instructed me how to take it.Yes it worked very well, after drinking it I went to the hospital for another test and everything turned negative. What a wonderful testimony I can never forget in my life. Dr Akhigbe is a man who gave me a life to live happily forever so all I want you all to believe and know that cure of HIV is real and herbs is a powerful medicine and it works and heals.  Dr Akhigbe also used his herbal medicine to cure diseases like:   HERPES, DIABETES, SCABIES, HEPATITIS A/B, STROKE, CANCER, ALS, TUBERCULOSIS, ASTHMA, PENIS ENLARGEMENT, MALARIA, LUPUS, LIVER CIRRHOSIS, DEPRESSION, HIV/AIDS, EPILEPSY, BACTERIAL, DIARRHEA, HEART DISEASES, HIGH BLOOD PRESSURE, PARKINSON'S, ALZHEIMER, COLD URTICARIA, HUMAN PAPILLOMAVIRUS,INSOMNIA,  BACTERIAL VAGINOSIS, SCHIZOPHRENIA, JOINT PAIN, STOMACH PAIN, CHROME DISEASES, CHLAMYDIA, INSOMNIA HEARTBURN, ,  THYROID, MAR BURG DISEASES, MENINGITIS, ARTHRITIS, BODY WEAK, SMALLPOX, DENGUE, FEVER, CURBS, CHANCRE, AND OTHERS VARIOUS DISEASES/ VIRUS.   You are there and you find yourself in any of these situations, kindly contact Dr Akhigbe now to help you get rid of it. Here is his email address:
       drrealakhigbe@gmail.com      or you can write to him on whats app with his phone number:   +2349010754824.
      My appreciation is to share his testimony for the world to know the good work Dr Akhigbe has done for me and he will do the same for you.
       

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  37. Here is  my testimony on how I was cured of HIV by Dr Akhigbe,with his natural herbal medicine.  on a regular basis in efforts to help others when I could. As you may know, each donation is tested.  Well, on July 6th I had a meeting with a Red Cross representative and was told that I had HIV. “What went through your mind when you heard that "Rose" Good question reader! To be honest, I thought my life was over, that I would ever find love, get married, have children or anything normal. Lucky for me I have an amazing support system.  My family supported me then I never thought that I was invincible to STD s or pregnancy or anything else parents warn their kids about. I just didn’t think about it. I was in a monogamous relationship and thought that I asked the right questions.  We even talked about marriage Scary.  During that time I was in college and donated blood on a re as well. who helped me in search of cure through the media.there we saw a good testimony of sister 'Kate' about the good work of Dr Akhigbe natural herbal medicine cure.then I copied his email address and contacted him. A good herbalist doctor with a good heart, he is kind, loving and caring. He replied back to my message and told me what to do. After a week the doctor sent me my herbal medicine and instructed me how to take it.Yes it worked very well, after drinking it I went to the hospital for another test and everything turned negative. What a wonderful testimony I can never forget in my life. Dr Akhigbe is a man who gave me a life to live happily forever so all I want you all to believe and know that cure of HIV is real and herbs is a powerful medicine and it works and heals.  Dr Akhigbe also used his herbal medicine to cure diseases like:   HERPES, DIABETES, SCABIES, HEPATITIS A/B, STROKE, CANCER, ALS, TUBERCULOSIS, ASTHMA, PENIS ENLARGEMENT, MALARIA, LUPUS, LIVER CIRRHOSIS, DEPRESSION, HIV/AIDS, EPILEPSY, BACTERIAL, DIARRHEA, HEART DISEASES, HIGH BLOOD PRESSURE, PARKINSON'S, ALZHEIMER, COLD URTICARIA, HUMAN PAPILLOMAVIRUS,INSOMNIA,  BACTERIAL VAGINOSIS, SCHIZOPHRENIA, JOINT PAIN, STOMACH PAIN, CHROME DISEASES, CHLAMYDIA, INSOMNIA HEARTBURN, ,  THYROID, MAR BURG DISEASES, MENINGITIS, ARTHRITIS, BODY WEAK, SMALLPOX, DENGUE, FEVER, CURBS, CHANCRE, AND OTHERS VARIOUS DISEASES/ VIRUS.   You are there and you find yourself in any of these situations, kindly contact Dr Akhigbe now to help you get rid of it. Here is his email address:
       drrealakhigbe@gmail.com      or you can write to him on whats app with his phone number:   +2349010754824.
      My appreciation is to share his testimony for the world to know the good work Dr Akhigbe has done for me and he will do the same for you.
       

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  38. I GOT CURED FROM HERPES VIRUS I was diagnosed of HERPES virus and i have tried all I can to get cured but all to no avail,,until I saw a post in a health forum about a herbalist man who prepare herbal medications to cure all kind of diseases including #HERPES virus,at first I doubted if it was real but decided to give it a try,when I contacted this herbalist via his email and he prepared a #HERPES herbal cure and sent it to me via DHL delivery company service, when I received this herbal medicine, he gave me step by direction on how to apply it,after applying the way I was instructed,I was totally cured of this deadly disease called HERPES, all thanks to Dr OGODO Email this great herbal doctor via his email Ogodoherbalhomesolution@gmail.com
    You can also WhatsApp him on +2349044680467
    HE CAN ALSO CURE SICKNESS LIKE
    {1}HIV/AIDS
    {2}DIABETES
    {3}EPILEPSY
    {4} BLOOD CANCER
    {5} HPV
    {6} ALS
    {7} HEPATITIS
    {8}LOVE SPELL
    {9} SICKLE AND ANEMIA
    Only DR OGODO Can Help You I Love You Father.

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  39. My name is Denial Edward, I want to thank Dr. Patrick who cast a SPELL that helped my family win a court case that would have sentenced my brother for life, who was charged with murder. My family and I are totally grateful. You can also contact him if you have a similar challenge on the email: drpatrickspelltample2001@gmail.com, he also cast a spell to win the lottery, get your ex-lover back, promotion spell, luck spell, coronavirus COVID 19, hiv cure / AIDS, cancer, spell to have children, etc.

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  40. A GREAT THANKS TO DR.WEALTHY FOR CURING ME FROM GENITAL HERPES I AM SO HAPPY TO GIVE THIS TESTIMONY ARE YOU SUFFERING FROM THIS SICKNESS HERE IS DR WHO CAN HELP
    I can’t believe my genital herpes is really cured, oh is by this time last year I start feeling bad about my life, I feel pain everyday of my life am very happy now that am really cured I couldn’t have do this on my own I wish is not God that help me with my helper I was searching the internet about this sickness last 3month when I found about great doctor wealthy, the man that keep his words I write the man email about my problem immediately I get a reply from him asking me to fill a form which I immediately did and send back to him after some mins he reply me that he have work on my cure that I need to provide some materials, which can enable him to work on my cure which I did on the next day of it, after some hours he inform me that he have getting the things needed for the cure and he is about to go on with the curing spell he called me again after 50mins that he is done with the cure that I should check my body and also go for test I cant believe I was negative a big thanks to him am very happy now with my family you can also get your self cured too from this sickness by contacting him through his email: wealthylovespell@gmail.com or whatapp +2348105150446 follow his instagram @wealthylovespell1 He also have a herbal cure for 7 other DISEASES;
    1.HIV
    2.SHINGLES
    3.VIRAL HEPATITIS
    4.INFLUENZA
    5.IMPOTENCE,
    6.BARENESS/INFERTILITY,
    7.ANTHRAX
    8 HPV
    Contact him today and you will have a testimony…Good luck!

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  41. I've been treating herpes virus for several years with different medications until I saw a post on how a young lady got cured from herpes, Out of desperation I decided to contact him with little or no hope of a solution after taken his herbal medications reluctantly to my biggest surprise I tested negative, God bless you Dr ubarlo drubarlohome@gmail.com or Whatsapp +2348119508814 for his wonderful work

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  42. months ago I felt some pains and I went to the hospital my doc told me I had Herpes about 1 year ago and I need to start the treatment early, he gave me some medicine to be taking and I told him no I’ll not, because I hated taking medicine when I won’t not see cure for the purpose. After I got home I started getting worried searching for strong advice and I found valid natural treatment online a lot of people says they got herpes cure from DR ODUDU and I contacted DR ODUDU that same day I purchase his cure online, after three weeks of taking the herbal treatment i got cured totally. i tested negative all thank to DR ODUDU you can reach out to him through his email: [dr.oduduherbalhome@gmail.com ] or message him on WhatsApp +2348101571054 stay safe and bless you

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  43. Nice post. Well what can I say is that these is an interesting and very informative topic on stomach ailments list

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